Modern logistics warehouse with advanced automation

3D Mapping and Navigation System to Improve outcome of the Renal Denervation Therapy

Our mission is to improve the management of non-responders and enhance the outcomes of the renal denervation procedure

33%
of people of the age of 30 have hypertension
20%
of patients with hypertension have side effects of antihypertensive drugs
10%
of patients have resistant arterial hypertension

What is Renal Denervation?

A new approach for the management of the arterial hypertension

Arterial hypertension

Hypertension is a major cause of premature death and the main risk factor for stroke, myocardial infarction, heart and kidney failure and vision loss.

  • 1.4 billion adults worldwide have hypertension
  • Patients must take medications daily
  • 10% of patients have resistant hypertension

Renal Denervation

Renal Denervation is a novel method for the treatment of hypertension. This is a minimally invasive endovascular catheter procedure for ablation of the the sympathetic nerves of the kidneys surrounding the renal arteries.

  • Effective
  • Save
  • Minimal Invasive

Problem of non-responders

Renal Denervation has proven to be safe. Catheters for procedure were approved in USA. However the therapy has a problem of non-responders.

  • 35% of non-responders
  • Problem of non-responsder stops adoptation of the technology
  • No solution on the market
Our solution

ReNavie Sensing 3D Mapping and Navigation

Our mission is significantly improve clinical outcome of the renal denervation procedure by providing a tool for systematic control of the ablation process.

Selective Ablation of Sympathetic Nerves

A method that ablates only sympathetic nerves while avoiding parasympathetic nerves.

Real-Time 3D Mapping and Navigation

Visualization of the renal anatomy along with the real-time position of the ablation catheter.

Highlighting the Sympathetic Ganglia

Addresses the issue of non-responders by correctly identifying the target areas for ablation.

Comprehensive Impedance Mapping

Provides precise response from electrical pacing to better control the outcome of the ablation procedure.

Advanced logistics technology dashboard

3D Mapping and Navigation

Sympathetic nerves selectivity

Compatible with any catheters
Insights from the clinical community

Renal Denervation Systems
Recieved FDA approval

Now the Renal Denervation is a part of 2003 ESH Guidelines for the management of arterial hypertension

ESH Guidelines recommend renal denervation as Class II for uncontrolled hypertension patients.

ESH Guidelines
ESH Guidelines
2023

European Society of Cardiology recommends renal denervation as an evidence-based treatment option for uncontrolled resistant hypertension.

European Heart Journal
European Heart Journal
2003

Based on data from the National Health and Nutrition Examination Survey (NHANES) (2009–2020), an estimated 21.5% of U.S. adults with hypertension would qualify for RDN under FDA indications.

Watson N, Earle W, et al.
Watson N, Earle W, et al.
2024, Circulation